Top 10 Spider-Man Villains (Ranked)

Top 10 Spider-Man Villains (Ranked)

One of the most beloved superheroes is none other than the red and blue web-slinging teenager, Spider-Man. He’s been New York City’s guardian for over 60 years. Throughout his career, he’s faced numerous villains, from petty criminals to murderous supervillains.

In this article, we’ll cover the top 10 Spider-Man villains who’ve caused him significant trouble. Feel free to let us know your favorites in the comments for future updates.

10. The Spot

Debuting in The Spectacular Spiderman#97 (1984), The Spot quickly gained popularity for his humorous approach to confrontations with Spider-Man. In the MCU Spider-Man movies, Spider-Man: Across The Spiderverse (2023) featured The Spot as the primary antagonist.

The Spot’s powers distinguish him from other villains. While many resort to destruction, he employs teleportation via portals to steal and evade capture. This subtle tactic adds to his allure. Additionally, his unconventional fighting style, utilizing portals to manipulate Spider-Man into self-inflicted harm, adds a comedic element to their encounters.

9. Kaine

Kaine is a complex character, often straddling the line between hero and villain. Despite occasional alliances with Spider-Man, he consistently reverts to his extreme tendencies.

8. Mister Negative

Debuting in The Amazing Spider-Man #546 (2008), Martin Li transformed into Mister Negative after a coerced drug experiment conducted by the Maggia crime family. Exposed to a synthetic drug called D-Lite, he became infused with Darkforce, becoming Mister Negative.

He clashed when attempting to seize control of New York City’s criminal underworld, deploying DNA-specific bioweapons named ‘The Devil’s Breath’ as depicted in the PS Spider-Man game. Spider-Man discovered and thwarted his scheme, sparking a bitter enmity between Mister Negative and Spider-Man.

7. Black Tarantula

Making his debut in The Amazing Spider-Man#419 (1997), Black Tarantula emerges as a formidable adversary of Spider-Man, known for his lethal tactics. Spider-Man regards him with fear, as Black Tarantula spares no brutality and readily resorts to deadly force, even in self-defense.

Top 10 Spider-Man Villains (Ranked)

Black Tarantula is a character Spider-Man considers formidable due to his speed and agility. However, Black Tarantula’s laser eyes can quickly reverse Spider-Man’s advantage.


Every superhero has a villain fueled by pure rage and violence. For Spider-Man, it’s Rhino. Unlike other villains, Rhino relies solely on brute force and fury.

Rhino often serves as a subordinate villain, utilized to hinder Spider-Man’s progress. Despite this, Rhino remains an entertaining presence in various media.


In his debut in The Amazing Spiderman#1 (1963), Chameleon became Spider-Man’s first foe. Despite arguments favoring other villains within Spider-Man’s universe, excluding Green Goblin, none match Chameleon’s cruelty. He is the half-brother of Sergie, also known as Kraven the Hunter, and is obsessed with avenging his brother’s death, blaming Spider-Man.

4. Hob Goblin

3. Venom

2. Doctor Octopus

Doctor Otto Octavius, a brilliant scientist, worked on a groundbreaking atomic energy project. He crafted four mechanical arms to aid his work. However, an accident fused these arms to his body, causing severe brain damage and transforming him into the criminal Doctor Octopus, a formidable foe of Spider-Man.

1. Green Goblin

Spider-Man has encountered numerous villains, some inflicting physical harm, while others causing emotional turmoil. Among these, Green Goblin stands out.

Green Goblin emotionally scarred Spider-Man by killing Gwen Stacy, his beloved, and targeting his family upon discovering his true identity. The unparalleled devastation inflicted by Green Goblin solidifies him as Spider-Man’s greatest adversary.